All about the Eversense CGM system

• Continuous Glucose Monitoring: The Game Changer
• What is Eversense CGM?
• The Eversense Difference: How Does It Work?
• The Eversense Edge: Key Features
• The Implantation Procedure
• The Removal and Replacement Process
• The Pros of Eversense
• The Cons of Eversense
• Balancing the Pros and Cons
• The Accuracy of Eversense
• Living with Eversense
• Not Just a Patch: Enhancing Your Eversense Experience
• Key Takeaways: The Eversense Advantage

The Eversense CGM is the CGM System that is making waves in the diabetes community. With its unique features and capabilities, Eversense is not just a product but a revolution in diabetes care. In this article, we’ll explore the captivating world of Eversense CGM, breaking down its features, benefits, and life-changing effects for its users.

Imagine a life where managing diabetes effortlessly blends into your daily routine, making the hassle of frequent finger pricks and abrupt sugar crashes a thing of the past. This isn’t just wishful thinking; it’s an achievable goal, courtesy of significant innovations in medical technology. The Continuous Glucose Monitoring (CGM) system is at the forefront of these advancements.

Continuous Glucose Monitoring: The Game Changer

Before we delve into the nuances of Eversense, it’s crucial to grasp what CGM is and why it revolutionizes diabetes care. As the name implies, Continuous Glucose Monitoring tracks your glucose levels around the clock. This is a significant leap from traditional blood glucose tests, which offer only isolated glimpses into your glucose state. CGM, on the other hand, gives you a continuous, real-time overview of your glucose variations.

Think about driving a car whose dashboard sporadically reveals your speed. Now, picture a dashboard that constantly displays your speed, complete with alerts for sudden changes. That illustrates the disparity between traditional glucose testing and CGM.

CGM systems document glucose levels at frequent intervals, generally every couple of minutes. This steady flow of information furnishes a detailed view of your glucose patterns, highlighting not just abrupt rises and falls but also the rate at which they happen. This holistic understanding is indispensable for effective diabetes management, enabling you to steer clear of both alarmingly high (hyperglycemia) and dangerously low (hypoglycemia) blood sugar levels.

What is Eversense CGM?

The Eversense CGM (Continuous Glucose Monitoring) system offers a unique alternative to traditional CGM devices. Unlike standard models, the Eversense sensor is implanted subcutaneously and lasts up to 90 days, delivering unmatched convenience and freedom for users.

Designed for adults aged 18 and over, the Eversense CGM system has been on the European market since May 2016 and received approval from the U.S. Food and Drug Administration (FDA) in June 2018. This pivotal achievement broadens the scope of diabetes management, unveiling fresh possibilities for those living with the condition.

The Eversense Difference: How Does It Work?

The Eversense CGM system operates using a unique combination of implanted sensor technology and an external transmitter. Let’s delve into the workings of this innovative system.

The Sensor: A Tiny Powerhouse

The Eversense CGM sensor is a tiny, transparent rod, thinner than a Tylenol tablet, designed to be implanted completely under the skin. The sensor is typically implanted in the upper arm, a location that is both convenient and discreet.

The sensor is coated with a fluorescent chemical. When glucose enters the bloodstream, the Eversense sensor instigates a chemical reaction that emits light. The brilliance of this light directly correlates with the glucose level in your blood. The sensor then captures and analyzes this light to furnish an accurate glucose reading. This ground-breaking use of light-based technology sets Eversense apart from conventional CGM systems.

The Transmitter: Your Constant Companion

The external transmitter serves as an essential component of the Eversense CGM system. Placed directly over the implanted sensor, this device adheres to the skin via a straightforward adhesive mechanism, making both application and removal a breeze.

The role of the transmitter within the Eversense system is crucial. It relays data to a specialized smartphone app at five-minute intervals, providing users with real-time insights into their glucose levels. This continual flow of information enables users to meticulously monitor their glucose levels, thereby making informed decisions about their diet, exercise, and medication.

Among the standout features of the Eversense transmitter is its adaptability. Feel free to detach and reattach it as needed. Such flexibility allows you to remove the transmitter for activities like showering or engaging in sports, without worrying about potential damage to the device or any loss of data. Once the activity is over, simply reattach the transmitter to resume the uninterrupted data feed to the app.

While the transmitter adds a layer of convenience, it does come with the minor caveat of requiring daily recharging—an inconsequential trade-off given its numerous benefits.

The Eversense CGM system is revolutionizing the way we approach diabetes management. Boasting a combination of long-lasting sensor technology and a user-friendly, adaptable transmitter, Eversense provides users with an unprecedented level of convenience and autonomy in managing their condition. This innovative system stands as a shining example of how technological advancement can transform healthcare. As we delve deeper into the features and advantages of the Eversense system, it becomes abundantly clear that it is raising the bar for diabetes care.

The Eversense Edge: Key Features

On-body vibration alerts: Vibration alerts on the body for high and low glucose levels
Predictive alerts: Predicts high or low glucose levels up to 30 minutes in advance
Sensor lifespan: Sensor lasts up to 90 days
Sensor implantation: Quick and simple implantation procedure
Transmitter flexibility: Transmitter can be removed and reattached as desired
Light-sensing technology: Uses light to measure glucose levels
Smartphone-only operation: Works with a companion smartphone app
Mobile app features: Offers a range of features for managing diabetes

The Eversense CGM system is packed with features that make it a standout choice in the world of diabetes management. Let’s explore these features in detail.

On-Body Vibration Alerts

One of the most distinctive features of the Eversense CGM system is its on-body vibration alerts. The Eversense transmitter vibrates on the body to alert users to high and low glucose levels. The intensity of the vibrations varies depending on glucose levels, providing a nuanced alert system that can be tailored to the user’s needs.

This feature offers a significant advantage in terms of discretion. Users can disable audio alerts if they choose, making the Eversense system a great choice for situations where silence is required or preferred. Whether you’re in a meeting, at the movies or simply enjoying some quiet time the Eversense system ensures that you can stay informed about your glucose levels without disturbing your peace.

Predictive Alerts

Another standout feature of the Eversense system is its predictive alerts. The system can predict when you’re going to experience high or low glucose levels up to 30 minutes in advance. These alerts can be delivered either via the on-body vibration feature or via the mobile app.

Predictive alerts are a powerful tool for managing diabetes. They provide a window of opportunity for users to take action before their glucose levels reach dangerous highs or lows. This can help to prevent serious health complications and provide peace of mind for users.

Sensor Lifespan

One of the most significant advantages of the Eversense CGM system is the extended lifespan of its sensor. Unlike traditional CGM sensors that typically need to be replaced every 7 to 10 days, the Eversense sensor is designed to last for up to 90 days. This extended lifespan means less frequent sensor changes, saving users time and reducing the discomfort associated with sensor insertion.

Recently the Eversense CGM system has taken a leap forward, with the latest version of the sensor now lasting up to 6 months. This advancement further enhances the convenience of the Eversense system, reducing the number of sensor changes per year from 26-52 to just 2. This means only two ‘Day 1′ warm-up periods per year, significantly reducing the disruption to users’ daily lives.

The extended lifespan of the Eversense sensor also eliminates some of the common hassles associated with traditional CGM systems. Users no longer have to worry about accidental sensor dislodging, wasting sensors when the transmitter is removed and replaced or the need for ongoing CGM supplies. The Eversense system offers a more streamlined and hassle-free approach to managing diabetes.

Sensor Implantation

The Eversense sensor is implanted under the skin in a quick procedure that takes less than 10 minutes. The sensor is typically implanted in the upper arm, a location that is both convenient and discreet. Once implanted the sensor has a one-time warmup period of 24 hours.

The sensor implantation is performed by a certified healthcare professional, ensuring a safe and smooth process. This professional insertion also eliminates the need for users to self-insert the sensor, a task that can be daunting for some.

Transmitter Flexibility

The Eversense transmitter is designed with user convenience in mind. It can be removed and reattached as often as desired, allowing for flexibility during activities like showering or sports. The transmitter needs to be recharged daily which can be done using a provided cable in just 10 to 15 minutes.

As mentioned before the removable transmitter also provides unique on-body vibration alerts, enhancing the user’s ability to stay informed about their glucose levels. This feature, combined with the extended sensor lifespan, makes a flexible and user-friendly solution for diabetes management.

Light-Sensing Technology

The Eversense system uses innovative light-based technology to measure glucose levels. The sensor is coated with a fluorescent chemical that reacts with glucose in the blood to produce light. The amount of light produced is measured by the sensor, providing a glucose reading.

This light-sensing technology offers a novel approach to glucose measurement, differentiating the Eversense system from other CGM systems on the market. It’s a prime example of how Eversense is pushing the boundaries of what’s possible in diabetes management technology.

Smartphone-Only Operation

The Eversense system is designed to work with a companion smartphone app. This means that users must have an Android or iOS device to use the system. The app provides a clear, easy-to-use interface for monitoring glucose levels, setting alert preferences, and viewing historical data.

Mobile App Features

The Eversense mobile app offers a range of features to help users manage their diabetes. These include a colored bar that shows glucose levels in relation to the target range, an alert history, an event log, and a range of reports that can be shared with healthcare providers or loved ones.

These key features make the Eversense CGM system a powerful tool for managing diabetes. With its unique combination of convenience, innovation, and user-friendly design, Eversense is changing the world of diabetes management.

The Implantation Procedure

The implantation of the Eversense sensor is a quick and straightforward procedure that takes place in a doctor’s office. It requires only a local anesthetic and takes less than 10 minutes. The sensor, a tiny transparent rod, is inserted into a pocket of skin about twice as deep as a regular CGM cannula would go. This is typically done in the upper arm, a location that is both convenient and discreet.

Once the sensor is implanted, it takes 24 hours to warm up. During this time the sensor begins to measure glucose levels and the user can start to receive data on their smartphone.

The Removal and Replacement Process

After 90 days (or 180 days with the E3 system) the sensor must be removed and a new one implanted. This is also done in a doctor’s office. The removal process is similar to the implantation procedure and is designed to be as painless and convenient as possible.

The new sensor is typically implanted in the other arm, allowing for rotation and reducing the risk of skin irritation or other complications. This rotation strategy is a key part of the Eversense system’s design, ensuring that users can continue to use the system comfortably and effectively over the long term.

The Pros of Eversense

Understanding the pros and cons can help potential users make an informed decision about whether this system is the right fit for their lifestyle and health needs.

Long-Term Glucose Monitoring

One of the most significant advantages of the Eversense CGM system is its long-term glucose monitoring capability. Unlike traditional CGM systems that require sensor replacements every 7 to 10 days, the Eversense sensor lasts up to 90 days. This extended lifespan reduces the need for frequent sensor changes, saving users time and reducing the discomfort associated with sensor insertion.

On-Body Vibration Alerts

The Eversense system offers on-body vibration alerts, a unique feature that sets it apart. The Eversense transmitter vibrates on the body to alert users to out-of-range events. The intensity of the vibrations varies depending on glucose levels, providing a high level of user customization. This feature allows users to disable audio alerts if they choose, offering a more discreet alert system.

Predictive Alerts

The Eversense system can predict when you’re heading in the direction of high or low glucose levels up to 30 minutes in advance. These predictive alerts can be delivered either via the on-body vibration feature or via the mobile app, providing users with the time needed to prevent significant glucose fluctuations.

Sensor Accuracy

The Eversense sensor boasts a mean absolute relative difference (MARD) of just 8.5%, making it one of the most accurate CGM systems on the market. This high level of accuracy can give users confidence in the glucose readings provided by the system.

User-Friendly Mobile App

The Eversense mobile app is easy to use and generates useful reports. Users can see their 90 days historical data, including trend graphs, right on the screen. The app also allows for variable alert settings and provides an alert history, making it easier for users to track and manage their glucose levels.

The Cons of Eversense

Daily Transmitter Charging

One potential downside of the Eversense system is the need to recharge the transmitter daily. This requirement might be inconvenient for some users, particularly those with busy schedules or those who travel frequently.

Oldschool Calibrations

Despite its advanced features the Eversense system still requires two finger pick calibrations per day as per FDA regulations. These calibrations help ensure the accuracy of the glucose readings provided by the system but they can be a hassle for some users.

Sensor Implantation and Removal

The Eversense sensor is implanted under the skin in a quick procedure that takes less than 10 minutes. However, this process requires a visit to a specialist healthcare provider who is trained in the Eversense system, which might not be ideal for everyone. Some users might find the need to schedule and attend these appointments inconvenient.

Transmitter Size

While the Eversense transmitter is smaller than some other CGM devices, it is still a noticeable presence on the body. Some users might find the size of the transmitter to be a drawback, particularly those who prefer a more discreet system.

Balancing the Pros and Cons

When considering the Eversense CGM system, it’s essential to weigh these pros and cons against your personal needs and lifestyle. While the system offers many advantages such as long-term glucose monitoring and predictive alerts, it also has potential downsides such as the need for daily transmitter charging and regular healthcare provider visits.

Ultimately the decision to use the Eversense CGM system should be made in consultation with your healthcare provider, taking into account your specific health needs, lifestyle, and personal preferences.

The Accuracy of Eversense

The Eversense CGM system is renowned for its high accuracy in glucose monitoring. It has a Mean Absolute Relative Difference (MARD) of 8.5% which is a measure of accuracy in CGM systems. The lower the MARD value the higher the accuracy of the CGM system. This makes Eversense one of the most accurate CGMs available in the US.

Understanding MARD

Before we delve deeper into the accuracy of Eversense, it’s important to understand what MARD is. MARD is a statistical measure used to determine the accuracy of glucose monitoring systems. It calculates the average difference between the CGM readings and the reference glucose value, typically obtained from a blood glucose meter. The lower the MARD value the closer the CGM readings are to the reference value and hence the more accurate the CGM system is.

Eversense’s High Accuracy

In the first video, the user mentions that the Eversense CGM readings were very close to the readings on their fingerstick meter which is considered a standard for glucose monitoring. This anecdotal evidence supports the high accuracy claimed by the Eversense CGM system.

When compared to other CGM systems, Eversense holds its ground in terms of accuracy. For instance, the Dexcom G6 has a MARD of 9.0% and the Freestyle Libre 2 has a MARD of 9.3%. This makes Eversense slightly more accurate than these popular CGM systems.

The Science Behind the Accuracy

The accuracy of the Eversense CGM system can be attributed to its unique light-sensing technology. The sensor is coated with a fluorescent chemical that, when exposed to blood sugar, produces a small amount of light that is measured by the sensor. This innovative approach to glucose monitoring allows Eversense to provide highly accurate readings.

Recent Studies on Eversense’s Accuracy

Recent studies and trials have further validated the high accuracy of the Eversense CGM system. The PROMISE study, an evaluation of an implantable continuous glucose sensor for up to 180 days, demonstrated the strong accuracy of the Eversense sensor. The study, published in June 2021, showed that the Eversense CGM system maintained its high accuracy over a longer sensor wear duration.

Another study, published in Diabetes Technology & Therapeutics in November 2020, compared the accuracy of the Dexcom G5, Abbott Freestyle Libre Pro, and Senseonics Eversense Continuous Glucose Monitoring Devices in a home-use study of subjects with Type 1 Diabetes. The results of the study further reinforced the high accuracy of the Eversense CGM system.

The high accuracy of the Eversense CGM system has significant implications for diabetes management. Accurate glucose readings allow for better decision-making regarding insulin dosing, diet, and physical activity. This can help prevent hypoglycemia and hyperglycemia, reducing the risk of diabetes-related complications.

Living with Eversense

Living with the Eversense CGM system involves some lifestyle considerations but it also offers a level of convenience and flexibility not found in other CGM systems.

One of the most common questions is whether you can shower with the Eversense CGM. The answer is yes, you can shower with the Eversense CGM sensor as this is under the skin. The transmitter that is worn on the skin is removable which means you can take it off whenever you want such as when you’re showering or swimming. After you’re done, you can simply put it back on.

In terms of other lifestyle considerations, the Eversense CGM system requires a small surgical procedure for sensor insertion every 180 days. This procedure must be done by a healthcare professional which means you need to plan around these appointments. However, as the Eversense system improves and extends its sensor lifetime, the advantage is that you only have to think about changing the sensor twice a year.

The Eversense CGM system also requires intermittent calibrations which means you have to do a manual fingerpicking blood glucose test. While this might be seen as a disadvantage compared to other CGM systems that do not require daily calibrations some users might appreciate the additional confirmation of the system’s accuracy.

Overall, living with the Eversense CGM system involves some adjustments but its long sensor life, removable transmitter, and high accuracy make it a viable option for many people with diabetes.

Not Just a Patch: Enhancing Your Eversense Experience

When it comes to managing diabetes, every detail matters. This includes the accessories you use with your Continuous Glucose Monitoring (CGM) system. One such accessory that can significantly enhance your Eversense transmitter experience is the Not Just a Patch (NJAP)  CGM adhesive patches.

NJAP patches are more than just a protective layer for your CGM system. They are designed with the user’s comfort and lifestyle in mind. These patches provide extra protection and security for your CGM system, ensuring it stays in place no matter what your day entails. Whether you’re hitting the gym, taking a swim, or simply going about your daily routine, NJAP patches keep your CGM system secure and functioning optimally.

Key Takeaways: The Eversense Advantage

The Eversense CGM system represents a significant advancement in diabetes management. It offers a unique approach to continuous glucose monitoring, providing long-term, accurate glucose readings with a level of convenience and flexibility not found in many other CGM systems.

The Eversense system’s long-lasting sensor, on-body vibration alerts, and predictive alerts are just a few of the features that set it apart. These features, combined with the convenience of a removable and rechargeable transmitter, make Eversense a standout choice for CGM.

Whether you’re new to CGM or looking for a change, Eversense could be a great fit for your lifestyle. It can provide you with the real-time glucose data you need to manage your diabetes effectively, while also fitting seamlessly into your daily routine.

However, as with any change to your diabetes management plan, it’s important to discuss the switch to Eversense with your healthcare provider. They can provide you with personalized advice and guidance, ensuring that Eversense is the right choice for your specific needs and circumstances.

With the right tools and information, managing diabetes can become an easy part of your daily life. The Eversense CGM system, (along with accessories like NJAP patches) can provide you with the technology and convenience you need to take control of your diabetes. By staying informed and proactive, you can live a healthy and fulfilling life with diabetes.

• https://www.ascensiadiabetes.com/eversense/
• https://global.eversensediabetes.com/
• https://www.fda.gov/medical-devices/eversense-e3-continuous-glucose-monitoring-system-p160048s016
• https://pubmed.ncbi.nlm.nih.gov/34515521/
• https://pubmed.ncbi.nlm.nih.gov/32453604/